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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPPA2
All Species:
16.06
Human Site:
Y1606
Identified Species:
44.17
UniProt:
Q9BXP8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXP8
NP_064714.2
1791
198539
Y1606
P
P
V
F
E
G
M
Y
E
C
T
N
G
F
S
Chimpanzee
Pan troglodytes
XP_514020
1791
198653
Y1606
P
P
V
F
E
G
M
Y
E
C
T
N
G
F
S
Rhesus Macaque
Macaca mulatta
XP_001095160
1573
175281
L1400
L
T
C
M
E
D
G
L
W
S
F
P
E
A
L
Dog
Lupus familis
XP_537179
1778
195855
Y1593
S
P
V
F
E
G
M
Y
E
C
T
N
G
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4K8
1624
181300
N1451
A
S
Q
G
R
G
S
N
I
I
H
C
R
K
D
Rat
Rattus norvegicus
XP_001073420
1788
198541
Y1603
P
P
V
F
E
G
M
Y
D
C
T
N
G
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426627
1551
171156
Q1378
Q
G
F
E
L
D
S
Q
C
V
L
S
C
E
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695417
1759
195473
Y1565
R
P
M
F
E
G
M
Y
S
C
T
N
N
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795597
1601
177169
V1428
Y
C
P
G
E
N
V
V
P
S
T
I
T
C
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
39.7
81.7
N.A.
43.6
79.4
N.A.
N.A.
57.9
N.A.
48
N.A.
N.A.
N.A.
N.A.
33.6
Protein Similarity:
100
99.7
56.3
89
N.A.
60
87.2
N.A.
N.A.
68.2
N.A.
63.8
N.A.
N.A.
N.A.
N.A.
49
P-Site Identity:
100
100
6.6
86.6
N.A.
6.6
86.6
N.A.
N.A.
0
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
6.6
86.6
N.A.
6.6
93.3
N.A.
N.A.
6.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% A
% Cys:
0
12
12
0
0
0
0
0
12
56
0
12
12
12
0
% C
% Asp:
0
0
0
0
0
23
0
0
12
0
0
0
0
0
23
% D
% Glu:
0
0
0
12
78
0
0
0
34
0
0
0
12
12
12
% E
% Phe:
0
0
12
56
0
0
0
0
0
0
12
0
0
56
0
% F
% Gly:
0
12
0
23
0
67
12
0
0
0
0
0
45
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
12
0
12
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% K
% Leu:
12
0
0
0
12
0
0
12
0
0
12
0
0
0
12
% L
% Met:
0
0
12
12
0
0
56
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
12
0
0
0
56
12
0
0
% N
% Pro:
34
56
12
0
0
0
0
0
12
0
0
12
0
0
12
% P
% Gln:
12
0
12
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
12
12
0
0
0
0
23
0
12
23
0
12
0
0
23
% S
% Thr:
0
12
0
0
0
0
0
0
0
0
67
0
12
0
12
% T
% Val:
0
0
45
0
0
0
12
12
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _